Chlamydia pneumoniae Infection Exacerbates Atherosclerosis in ApoB100only/LDLR^−/− Mouse Strain

Figure 5

Plasma lipid levels in the mice. Plasma samples of ApoB100only/LDLR^−/− and ApoE^−/− mice taken at 1 week after the first (1x), second (2x), and third (3x) Cpn infection and at the end of the experiment (week 12) and from the noninfected control mice at the same time points were tested for concentration of (a) total cholesterol, (b) triglyceride, (c) LDL, and (d) HDL content. Lipid concentrations are expressed as mmol/L; mean of values measured in individual mouse sera (ApoB100only/LDLR^−/− noninfected (), Cpn-infected (), and ApoE^−/− mice noninfected (), Cpn-infected ()), and standard deviations (SD) are shown; independent-samples -test was used, . The figure demonstrates the results of one of two independent experiments.

(a)

(b)

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(d)