Research Article

Basic Fibroblast Growth Factor Fused with Tandem Collagen-Binding Domains from Clostridium histolyticum Collagenase ColG Increases Bone Formation

Figure 5

Analysis of 3D micro-CT images of mouse femurs four weeks after injection of poly(Pro-Hyp-Gly)10 loaded with bFGF and CB-bFGFs into femoral fracture sites. We analyzed 3D images created from 10 mm regions (500 slices) from the mid-femur using Tri-3D-Bon 3D image analysis software four weeks after creation of the fracture. (a) Callus volume (mm3) and (b) bone mineral content (mg). Data are presented as the mean ± SE . compared with the control group. compared with the bFGF group. compared with the bFGF-s3 group. compared with the bFGF-s2b-s3 group. compared with the bFGF-s3b group.
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