High Incidence of Gastrointestinal Ulceration and Cytogenetic Aberration of Trisomy 8 as Typical Features of Behçet’s Disease Associated with Myelodysplastic Syndrome: A Series of 16 Consecutive Chinese Patients from the Shanghai Behçet’s Disease Database and Comparison with the Literature

Table 2

Symptoms and laboratory findings in patients with intestinal BD according to MDS.

	Intestinal BD with MDS ()	Intestinal BD without MDS ()
Age at diagnosis of intestinal BD (years)	49.5 ± 12.8	37.7 ± 13.7	0.00
Male (%)	2 (20.0)	54 (57.4)	0.04
Duration (months)	178 ± 58	107 ± 126	0.129
Systemic signs
Oral ulcer	10 (100)	90 (95.7)	>0.99
Genital ulcer	8 (80.0)	66 (70.2)	0.708
Ocular lesion	0 (0)	3 (3.2)	>0.99
Arthritis	3 (30.0)	22 (23.4)	0.694
Skin lesions	4 (40.0)	42 (44.7)	>0.99
Positive pathergy test	3 (30.0)	20 (21.3)	0.608
Central nervous system	0 (0)	0 (0)	-
Symptoms of GI involvement
Abdominal pain	7 (70.0)	82 (87.2)	0.184
Melena/hematochezia	4 (40.0)	30 (31.9)	0.717
Diarrhea	5 (50.0)	46 (48.9)	>0.99
Weight loss	8 (80.0)	44 (46.8)	0.083
Fever	6 (60.0)	8 (8.5)	0.00
Perforation	0 (0)	8 (8.5)	>0.99
Ileus	1 (10.0)	8 (8.5)	>0.99
Location of intestinal ulcers
Esophagus	0 (0)	18 (19.1)	0.336
Ileocecal	9 (90.0)	46 (48.9)	0.03
Small intestine	1 (10.0)	6 (6.4)	0.548
Colon	1 (10.0)	24 (25.5)	0.426
Laboratory findings at BD diagnosis
CRP (mg/L)	63.3 ± 41.4	20.7 ± 28.4	0.01
ESR (mm/h)	91.9 ± 21.5	129.4 ± 21.9	<0.00
WBC (10^9/L)	3.7 ± 2.5	6.8 ± 2.9	0.00
Hemoglobin (g/L)	89.7 ± 17.7	129.4 ± 19.9	<0.00
Platelets (10^9/L)	163.9 ± 116.4	243.1 ± 92.7	0.02

. BD: Behçet disease; GI: gastrointestinal; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; WBC: white blood cells.