Research Article

Antidiabetic and Antiobesity Effects of Artemether in db/db Mice

Figure 3

Effects of artemether on insulin resistance in db/db mice. At the beginning and the end of the treatment, intraperitoneal insulin tolerance tests (IPITT) (0.5 U/kg), and insulin levels were performed after 2 h of fasting. (a) Fasting insulin levels. (b) HOME-IR. (c) shows the result of IPITT of mice at the start of experiment. (d) shows the area under the curve from the insulin tolerance test described in (c). (e) shows IPITT of mice after the treatment of artemether. (f) shows the area under the curve from the insulin tolerance test described in (e). Values are mean and SEM for four-five mice. , versus NC group, and , versus DM group in (d).
(a)
(b)
(c)
(d)
(e)
(f)