Discriminative and Quantitative Analysis of Antineoplastic Taxane Drugs Using a Handheld Raman Spectrometer

Table 1

Performance of Raman calibration models for quantification developed for the entire concentration ranges. This table shows the characteristics of the calibration models with the number of spectra used to develop and validate models (n) and the number of latent variables (nLVs) considered when developing the calibration model. This table also lists the results of predictive performances including the coefficient of determination (R²), root mean square of cross-validation (RMSECV), and the root mean square error of prediction (RMSEP) for calibration models.

	CBX	PCX	DCX
Concentration range investigated (mg/mL)	0.05–0.30	0.24–1.20	0.2–1.00
Data pre-processing	Raw	Raw	SNV
nLVs	12	4	6
RMSECV (mg/mL)	0.014	0.084	0.055
RMSEP (mg/mL)	0.012	0.041	0.048
R^2	0.9999	0.9598	0.9916