Protocol for Fecal Microbiota Transplantation in Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis

Table 3

RCTs of FMT in UC.

	Costello et al [41].	Moayyedi et al [14].	Paramsothy et al [15].	Rossen et al [16].
Number	73(38 FMT/35 placebo)	75(38 FMT/37 placebo)	81(41 FMT/40 placebo)	48(23 FMT/25 placebo)
Severity	mild-moderate	mild-moderate	mild-moderate	mild-moderate
Route	colonoscopy and enema	enema	colonoscopy and enema	nasoduodenal
Placebo	Autologous stool	water	water	Autologous stool
Donor	unrelated	unrelated	unrelated	unrelated
Fresh vs Frozen	Frozen	frozen and fresh	Frozen	Fresh
Frequency	3	6	40(5x/week for 8 weeks)	2
Follow-up	8 weeks	6 weeks	8 weeks	12 weeks
Remission	12/38(FMT)	9/38(FMT)	11/41(FMT)	7/23(FMT)
FMT/placebo	3/35(placebo)	2/37(placebo)	3/40(placebo)	5/25(placebo)
Response	21/38(FMT)	15/38(FMT)	22/41(FMT)	11/23(FMT)
FMT/placebo	7/35(placebo)	9/37(placebo)	9/40(placebo)	13/25(placebo)