Research Article

Uncontrolled Diabetes Mellitus Has No Major Influence on the Platelet Transcriptome

Table 2

Multiplate electric impedance and light transmission aggregometry. TRAP: thrombin receptor-activating peptide, ADP: adenosine-diphosphate, HS: high-sensitivity, and AU: area under the curve.

Diabetes no Diabetesp
(Mann-Whitney-U-test)

Multiplate electric impedance aggregometry
 TRAPtest (AUmin)748 721-1241941 924-10190.690
 ADPtest (AUmin)707 520-741696 692-7180.841
 ADPtest HS (AUmin)607 400-610509 461-5681
 ASPItest (AUmin)342 188-346413 255-5990.518
Light transmission aggregometry
 TRAP 25μM (% aggregation)85 84-86100 100-1000.087
 ADP 5μM (% aggregation)47 34-4966 44-720.310
 ADP 20μM (% aggregation)82 67-8488 74-940.548
 Arachidonic acid 500mg/l (% aggregation)7 7-109 6-960.802
 Collagen 1mg/l (% aggregation)10 10-1118 14-740.016
 Collagen 2.5mg/l (% aggregation)28 23-4360 39-1000.103