The Plant Proteinase Inhibitor CrataBL Plays a Role in Controlling Asthma Response in Mice

Table 3

Absolute values of morphometric and optical density measurement analysis for inflammatory, remodeling, and oxidative stress markers in the alveolar walls. Eight animals per group were used for these analyses. P<0.05 compared to OVA+CR, C and C+CR groups; † P<0.05 compared to C and C+CR groups.

Inflammatory Markers	C	OVA	C+CR	OVA+CR
Eosinophils (cells/10^4m^2)	0.34±0.21	5.67±0.60	0.30±0.18	2.45±0.70 †
IL-4 (cells/10^4m^2)	0.61±0.20	12.27±0.82	0.54±0.39	5.22±0.71 †
IL-5 (cells/10^4m^2)	0.95±0.38	13.76±0.93	1.03±0.49	4.40±0.57 †
IL-13 (cells/10^4m^2)	0.90±0.44	7.71±1.21	0.48±0.32	3.66±1.49
IL-17 (cells/10^4m^2)	1.25±0.31	12.20±0.91	1.10±0.06	6.23±0.55†
IFN- (cells/10^4m^2)	0.90±0.44	14.50±1.34	0.93±0.43	5.92±1.30 †
Remodeling Markers	C	OVA	C+CR	OVA+CR
Collagen Fibers (%)	2.97±0.29	12.89±0.90	2.88±0.40	5.69±0.70 †
Elastic Fibers (%)	5.52±0.37	12.15±0.47	5.78±0.25	8.32±0.43 †
MMP-9 (cells/10^4m^2)	0.68±0.46	9.32±1.18	1.03±0.48	3.51±0.86
TIMP-1 (cells/10^4m^2)	0.68±0.46	9.32±1.18	1.03±0.48	4.80±1.30 †
TGF- (cells/10^4m^2)	0.66±0.41	13.51±0.93	0,64±0.43	6.92±0.90 †
Mechanism	C	OVA	C+CR	OVA+CR
NF-B (cells/10^4m^2)	0.58±0.40	10.02±0.87	0.42±0.26	3.88±0.75 †