Research Article

Peripheral Blood Lymphocyte-to-Monocyte Ratio as a Useful Prognostic Factor in Newly Diagnosed Multiple Myeloma

Table 1

Characteristics at baseline of 285 newly diagnosed MM patients.

CharacteristicAll cases (n=285)LMR 4.2 (n=132)LMR > 4.2 (n=153)P

Age at diagnosis, years0.478
 < 6519794103
65883850
Gender0.200
 Male1597980
 Female1265373
Hemoglobin0.878
100g/L1265967
 < 100g/L1597386
Serum albumin0.073
35g/L1015447
 < 35g/L18478106
Serum LDH0.001
 < 250U/L23696140
250U/L493613
Serum creatinine0.006
 < 177umol/L235100135
177umol/L503218
Serum calcium0.003
 < 2.75mmol/L266117149
2.75mol/L19154
Serum β2-microglobulin0.035
 < 5.5mg/L17271101
 ≥5.5mg/L1136152
1q21 gain0.851
 Negative1557184
 Positive1306169
del (17p)0.790
 Negative252116136
 Positive331617
t (4;14)0.080
 Negative246119127
 Positive391326
t (11;14)0.018
 Negative229114115
 Positive561838
t (14;16)0.953
 Negative274127147
 Positive1156
Relapse0.001
 No17670106
 Yes835132
ASCT
 No196921040.798
 Yes894049

Abbreviations: ASCT, autologous stem cell transplantation; LDH, lactate dehydrogenase; LMR, lymphocyte-to-monocyte ratio; MM, multiple myeloma.