Research Article
Peripheral Blood Lymphocyte-to-Monocyte Ratio as a Useful Prognostic Factor in Newly Diagnosed Multiple Myeloma
Table 1
Characteristics at baseline of 285 newly diagnosed MM patients.
| Characteristic | All cases (n=285) | LMR 4.2 (n=132) | LMR > 4.2 (n=153) | P |
| Age at diagnosis, years | | | | 0.478 | < 65 | 197 | 94 | 103 | | 65 | 88 | 38 | 50 | | Gender | | | | 0.200 | Male | 159 | 79 | 80 | | Female | 126 | 53 | 73 | | Hemoglobin | | | | 0.878 | 100g/L | 126 | 59 | 67 | | < 100g/L | 159 | 73 | 86 | | Serum albumin | | | | 0.073 | 35g/L | 101 | 54 | 47 | | < 35g/L | 184 | 78 | 106 | | Serum LDH | | | | 0.001 | < 250U/L | 236 | 96 | 140 | | 250U/L | 49 | 36 | 13 | | Serum creatinine | | | | 0.006 | < 177umol/L | 235 | 100 | 135 | | 177umol/L | 50 | 32 | 18 | | Serum calcium | | | | 0.003 | < 2.75mmol/L | 266 | 117 | 149 | | 2.75mol/L | 19 | 15 | 4 | | Serum β2-microglobulin | | | | 0.035 | < 5.5mg/L | 172 | 71 | 101 | | ≥5.5mg/L | 113 | 61 | 52 | | 1q21 gain | | | | 0.851 | Negative | 155 | 71 | 84 | | Positive | 130 | 61 | 69 | | del (17p) | | | | 0.790 | Negative | 252 | 116 | 136 | | Positive | 33 | 16 | 17 | | t (4;14) | | | | 0.080 | Negative | 246 | 119 | 127 | | Positive | 39 | 13 | 26 | | t (11;14) | | | | 0.018 | Negative | 229 | 114 | 115 | | Positive | 56 | 18 | 38 | | t (14;16) | | | | 0.953 | Negative | 274 | 127 | 147 | | Positive | 11 | 5 | 6 | | Relapse | | | | 0.001 | No | 176 | 70 | 106 | | Yes | 83 | 51 | 32 | | ASCT | | | | | No | 196 | 92 | 104 | 0.798 | Yes | 89 | 40 | 49 | |
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Abbreviations: ASCT, autologous stem cell transplantation; LDH, lactate dehydrogenase; LMR, lymphocyte-to-monocyte ratio; MM, multiple myeloma.
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