Baseline Predictors of Visual Acuity Outcome in Patients with Wet Age-Related Macular Degeneration

Table 1

Prognostic impact of OCT imaging in patients with wAMD.

Anatomical structure	Significant findings	Relevant to the clinical outcome
Ellipsoid zone (EZ)	Absence or disruption	Highly correlated to visual outcome
External limiting membrane (ELM)	Interruption	A sign of damage of inner segment of cell bodies of photoreceptors
Foveal retinal thickness (FRT)	Thicker than normal	Controversial
Features of retinal and RPE layers	Presence of intraretinal fluid	Poorer VA outcome; Increase the risk of geographic atrophy
Baseline choroidal thickness (CT)	Thicker subfoveal choroidal thickness	Poorer VA outcome
Retinal pigment epithelium (RPE)	Double layer sign	A predictor of PCV, higher risk of nonresponse to anti-VEGF therapy

wAMD: wet age-related macular degeneration.