Research Article

Autophagy Is Independent of the Chondroprotection Induced by Platelet-Rich Plasma Releasate

Figure 6

Effect of PRP on traumatic injury of articular cartilage in vivo. Three weeks after the cut of medial meniscus, rats (8 in every group) were received intra-articular injection of L-PRP or P-PRP releasate once a week for 3 weeks. (a) Representative images of tissue sections through the tibiofemoral joint stained with the Safranin O. Images were acquired at a magnification of 100x. Scale bars: 500 μm. (b) Histograms showing the mean cartilage degeneration scores of the sham, MMT, and PRP-treated joints. (c, d) The expression of LC3 was assessed by immunochemical staining. represents significant difference versus the sham group; # represents significant difference versus the MMT group. MMT: medial meniscus tear.
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