BioMed Research International / 2019 / Article / Fig 4

Research Article

Resveratrol Suppresses Epithelial-Mesenchymal Transition in GBM by Regulating Smad-Dependent Signaling

Figure 4

Resveratrol (Res) inhibits EMT generated stem cell-like properties of GBM cells. (a) Resveratrol (40μM) inhibited EMT-induced gliosphere formation. Representative images of gliosphere were photographed under Olympus microscope (×100 magnification). The numbers of gliosphere in different treatment groups were showed in histograms. (b) Western blotting showed that resveratrol inhibited EMT-induced upregulation of stemness-related proteins expression in a dose-dependent manner. Each independent experiment was repeated three times.


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