BioMed Research International / 2019 / Article / Fig 5

Research Article

Resveratrol Suppresses Epithelial-Mesenchymal Transition in GBM by Regulating Smad-Dependent Signaling

Figure 5

Resveratrol inhibits EMT by regulating Smad-dependent signaling. (a) Western blotting showed that resveratrol inhibited EMT-induced upregulation of p-Smad2(Ser465+Ser467)/p-Smad3(Ser423+Ser425) expression in a dose-dependent manner. (b) Western blotting showed that LY2109761 inhibited EMT-induced upregulation of p-Smad2(Ser465+Ser467)/p-Smad3(Ser423+Ser425) expression and inhibited EMT-induced upregulation of N-cadherin, β-catenin, Vimentin, and Twist1 expression. All samples were analyzed in triplicate.

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