BioMed Research International / 2019 / Article / Tab 2

Research Article

Bromodomain and Extraterminal (BET) Protein Inhibition Restores Redox Balance and Inhibits Myofibroblast Activation

Table 2

NOX4 and SOD2 gene expression data extracted from microarray analysis.

GeneControl
(n=10)
SSc-ILD
(n=8)
Fold changep valueIPF
(n=3)
Fold changep value

NOX412.3206.616.90.012323.626.40.016

SOD22180.4311.0-7.0<1x10−629.8-73.2<1x10−6

Basal serum-free gene expression in non-ILD control, SSc-ILD, and IPF lung fibroblasts was determined by Affymetrix microarray analysis [27]. Mean expression levels are given in Affymetrix units. Fold changes for SSc-ILD and IPF fibroblasts, and p values adjusted for multiple comparisons, are relative to the expression levels in non-ILD control cells.

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