Gender-Related Effect of Sodium Dichloroacetate on the Number of Hassall’s Corpuscles and RNA NKCC1 Expression in Rat Thymus

Figure 2

Morphological changes of rat thymus: a comparison of the male gonad-intact control and the male castrated control groups. (a) the male gonad-intact control group; (b) the male castrated control group (size of the male thymus increased after castration); (c) Hassall’s corpuscles are not present in the male gonad-intact control rat thymus; thymic epithelial cells are positive for high molecular weight cytokeratins (clone 34βE12). Streptavidin-biotin-peroxidase, hematoxylin counterstain; (d) Hassall’s corpuscles (arrows) are present in the medullar region of thymus in the male castrated control group and positive for high molecular weight cytokeratins. Scale bar: 1 mm (a and b), 50 μm (c and d).

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