BioMed Research International / 2019 / Article / Fig 2

Research Article

A 6-Gene Risk Signature Predicts Survival of Glioblastoma Multiforme

Figure 2

Coexpression modules revealed by weighed gene co-expression network analysis (WGCNA). (a) Determination of soft threshold for adjacency matrix. The horizontal axis represents the soft threshold power and the vertical axis represents the square of the correlation coefficient of between and . The red line indicates where the correlation coefficient is 0.9, and the corresponding soft threshold power is 18. (b) Plots of mean connectivity versus soft threshold. The red line indicates where power is 18, and the corresponding mean connectivity is 1.0. (c) Gene dendrogram derived from hierarchical clustering. Different modules are indicated by colors underneath the dendrogram. (d) Module-trait relationships. Along the vertical axis are the modules represented by different colors. Correlation coefficients are shown as numbers in corresponding positions and p values are shown in brackets along the coefficients. (e) Heatmap of DEGs in blue (left) and yellow (right) modules. Tumor and normal samples are represented as dark and white bar, respectively. Upregulated and downregulated DEGs are shown in red and green, respectively.


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