Independent Influence of Blood Pressure on QTc Interval: Results from a General Chinese Population

Table 3

Logistic regression analyses for association between hypertension and prolonged QTc interval.

Group	Prolonged QTc	Model 1		Model 2		Model 3
	n (%)	OR (95% CI)	P value	OR (95% CI)	P value	OR (95% CI)	P value
Total
Normotension	389 (7.5)	1		1		1
Hypertension	982 (18.4)	2.48 (2.17–2.82)	< 0.001	1.79 (1.55–2.07)	< 0.001	1.71 (1.48–1.98)	< 0.001
Male
Normotension	120 (5.4)	1		1		1
Hypertension	416 (16.3)	2.99 (2.40–3.72)	< 0.001	2.14 (1.69–2.72)	< 0.001	2.03 (1.60–2.59)	< 0.001
Female
Normotension	269 (9.0)	1		1		1
Hypertension	566 (20.3)	2.23 (1.89–2.63)	< 0.001	1.63 (1.36–1.95)	< 0.001	1.56 (1.30–1.88)	< 0.001

Abbreviations. CI: confidence interval; OR: odds ratio; QTc: QT interval corrected for heart rate with Bazett’s formula.
Note. Model 1: adjusted for age, gender, and race; Model 2: additional adjustments for BMI, FBG, TC, TG, LDL-C, HDL-C, SUA, current smoking, drinking status, serum calcium, potassium and magnesium, heart rate, history of heart disease, and any medication used; Model 3: additional adjustments for LVH.