Figure 7: KEGG pathways significantly enriched in the predicted target genes of differentially expressed miRNAs. Advanced bubble chart shows enrichment of differentially expressed genes in signaling pathways. y-axis represented pathway, and x-axis represented rich factor, which meant the ratio of the amount of differentially expressed genes enriched in the pathway and the amount of all genes annotated in this pathway. Size and color of the bubble represented the amount of differentially expressed genes enriched in the pathway and enrichment significance, respectively.