BioMed Research International / 2019 / Article / Tab 1

Research Article

AVE 0991 Attenuates Pyroptosis and Liver Damage after Heatstroke by Inhibiting the ROS-NLRP3 Inflammatory Signalling Pathway

Table 1

Characteristics of heatstroke patients according to liver function.

ParametersHepatic
dysfunction
(n= 28, 40.6%)
Non-hepatic dysfunction
(n=41,59.4%)
P value

Ang II (pg/ml)145.59(44.56-406.98)39.75(33.32-54.75)<0.001
Ang-(1-7) (pg/ml)398.53±257.26718.59±302.87<0.001
Ang II/ Ang-(1-7) ratio0.38(0.12-1.57)0.07(0.04-0.12)<0.001
Length of ICU stay (days)8(2-49)3(3-5)<0.001
Organ support (yes/no)14/144/37-
Death (yes/no)8/200/41-

Ang II, angiotensin II; Ang-(1-7), angiotensin-(1-7); Organ support: invasive mechanical ventilation, haemopurification or haemodynamic support. Non-normally distributed data are expressed as median (25th percentiles, 75th percentiles) or percentages; “-”, chi-square tests are invalid because of small incidence in the non-hepatic dysfunction group.

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