Muscle Atrophy Marker Expression Differs between Rotary Cell Culture System and Animal Studies
Average ± s.d. fold change in expression of mRNAs for alginate and microcarrier cultures, relative to their respective normal gravity controls (alginate N=4, microcarrier N=20) and normalized by GAPDH. p<0.05, p<0.01, and p<0.001. No marker = not significant. N=4 (alginate differentiated), N=4 (alginate undifferentiated), N=16 (RCCS), and N=8 (ULA T25 + RCCS). All replicates are biological replicates and significance was determined by t-test.