The Risk of Retinopathy of Prematurity in the Infants following Assisted Reproductive Technology: A Meta-Analysis

Table 2

Summary of subgroup analysis of the meta-analysis results. RE: random effects; FE: fixed effects. IVF: in vitro fertilization; ART: assisted reproductive technology.

Groups	Studies	Test of association				Heterogeneity
		OR [95%CI]	p value	Model	Z	X^2	p value	I^2(%)
Total studies	15	1.34 [1.05-1.73]	0.02	RE	2.32	37.64	0.001	63
Subgroup analysis
Study design
Cohort	7	1.28 [0..96-1.70]	0.09	RE	1.69	14.45	0.025	59
Case-control	3	0.9 [0.65-1.25]	0.53	FE	0.62	0.51	0.777	0
Cross-sectional	5	2.39 [1.07-5.33]	0.03	RE	2.13	15.17	0.004	74
Region
Asia	4	1.33 [0.92-1.91]	0.13	RE	1.51	10.47	0.015	71
Europe	5	1.83 [0.7-4.82]	0.22	RE	1.23	19.75	0.001	80
America	6	1.10 [0.90-1.36]	0.34	FE	0.94	5.37	0.372	7
IVF and ART
IVF	7	1.73 [1.19-2.51]	0.004	RE	2.87	24.79	0.004	76
ART	8	0.97 [0.76-1.23]	0.8	FE	0.25	9.07	0.247	23