Clinical Study

The Effects of Oral Isotretinoin in Women with Acne and Polycystic Ovary Syndrome

Table 1

Evaluation of ovarian reserve, hirsutism, and acne scoring.

Pre-treatment n=40Post-treatment n=40P-value

Modified Ferriman-Gallwey Score11,75 ± 4,0711,08 ± 3,740,011
Acne Scoring2(2-3)0(0-0,75)<0,001
Ovarian volume right11(8-13)9(7-11,75)0,026
Ovarian volume left10,5(8-13,75)8(7-10,75)0,018
Follicle count right10(9-11)7(6,25-8)<0,001
Follicle count left9,88 ± 2,286,3 ± 1,71<0,001

To test the normality assumption of the data, Shapiro Wilk was used. Values are expressed as mean ± standard deviation or median (25th percentile – 75 percentile). Parametric comparisons were made with t-test for two dependent groups; non-parametric comparisons were made with Wilcoxon Signed Ranks test. PASW Statistics 18 program was used for all comparisons. p<0.05 probability value was considered as statistically significant.