The Additional Effect of Autologous Platelet Concentrates to Coronally Advanced Flap in the Treatment of Gingival Recessions: A Systematic Review and Meta-Analysis

Table 1

General information of enrolled articles.

References (year)	Study Design; (Duration)		Population			Miller Class	Site of Recessions	Intervention (No. of sites)
		Sample size	Sex	Age	Smoking			Test	Control
		(No. of patients)		(Range)	(Yes, No?)
Huang et al. (2005)	RCT/parallel	23 sites (23)	17F/6M	43.8±11.9	No	I	Maxillary or mandibular	CAF + PRP (11)	CAF (12)
	(6 months)						anterior and premolar teeth,
Padma et al. (2013)	RCT/split-mouth	30 sites (15)	NR	18~35	No	I and II	NR	CAF+PRF (15)	CAF (15)
	(6 months)
Thamaraiselvan et al.	RCT//parallel	20 sites (20)	2F/18M	21~47	No	I and II	Maxillary or mandibular	CAF+PRF (10)	CAF (10)
(2015)	(6 months)						anterior and premolar teeth,
Bozkurt et al. (2015)	RCT/split-mouth	119 sites (20)	13F/7M	37.10±1.03	No	I and II	NR	CAF+CGF (60)	CAF (59)
	(6 months)
Gupta et al. (2015)	RCT/split-mouth	30 sites (26)	NR	20~50	No	I and II	Maxillary anterior and	CAF+PRF (15)	CAF (15)
	(6 months)						premolar teeth,
Biradar et al. (2015)	RCT/ parallel	30 sites (30)	NR	18~45	No	I and II	Maxillary or mandibular anterior,	CAF+PRP (15)	CAF (15)
	(4 months)						premolar and molar teeth,
Kuka et al. (2017)	RCT/split-mouth	52 sites (24)	13F/11M	32.35±6.41	No	I	Maxillary or mandibular	CAF+PRF (28)	CAF (24)
	(12 months)						anterior and premolar teeth,
Dixit et al. (2018)	RCT/split-mouth	24 sites (12)	5F/7M	18~50	No	I and II	NR	CAF+PRF (12)	CAF (12)
	(6 months)

NR: Not Reported CAF: Coronally Advanced Flap PRP: Platelet-Rich Plasma PRF: Platelet-Rich Fibrin CGF: Concentrated Growth Factor.