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BioMed Research International
Volume 2019, Article ID 2590563, 7 pages
Research Article

Impact of Healthcare-Associated Infections on Length of Stay: A Study in 68 Hospitals in China

1Peking University First Hospital, Beijing 100034, China
2Shandong Provincial Hospital, Jinan 250021, China
3Guangdong General Hospital, Guangzhou 510008, China
4The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China
5The First Hospital, Shanxi Medical University, Taiyuan 030001, China
6Xiangya Hospital, Central South University, Changsha 410008, China
7General Hospital of PLA, Beijing 100853, China
8The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
9Guizhou Provincial People’s Hospital, Guiyang 550002, China
10Jiangxi Provincial Children’s Hospital, Nanchang 330006, China
11Fourth Hospital of Hebei Medical University, Shijiazhuang 050019, China
12Jiangsu Province Hospital, Nanjing 210029, China
13Peking University People’s Hospital, Beijing 100044, China
14The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China
15Inner Mongolia People’s Hospital, Hohhot 010017, China
16Heilongjiang Provincial Center for Disease Control and Prevention, Harbin 150030, China

Correspondence should be addressed to Liuyi Li; ten.362@iyuilycul

Received 20 February 2019; Accepted 11 April 2019; Published 18 April 2019

Guest Editor: Yatao Liu

Copyright © 2019 Huixue Jia et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Healthcare-associated infections (HAIs) not only bring additional medical cost to the patients but also prolong the length of stay (LOS). 2119 HAI case-patients and 2119 matched control-patients were identified in 68 hospitals in 14 primary sampling provinces of 7 major regions of China. The HAI caused an increase in stay of 10.4 days. The LOS due to HAI increased from 9.7 to 10.9 days in different levels of hospitals. There was no statistically significant difference in the increased LOS between different hospital levels. The increased LOS due to HAI in different regions was 8.2 to 12.6 days. Comparing between regions, we found that the increased LOS due to HAI in South China is longer than other regions except the Northeast. The gastrointestinal infection (GI) caused the shortest extra LOS of 6.7 days while the BSI caused the longest extra LOS of 12.8 days. The increased LOS for GI was significantly shorter than that of other sites. Among 2119 case-patients, the non-multidrug-resistant pathogens were detected in 365 cases. The average increased LOS due to these bacterial infections was 12.2 days. E. coli infection caused significantly shorter LOS. The studied MDROs, namely, MRSA, VRE, ESBLs-E. coli, ESBLs-KP, CR-E. coli, CR-KP, CR-AB, and CR-PA were detected in 381 cases (18.0%). The average increased LOS due to these MDRO infections was 14 days. Comparing between different MDRO infections, we found that the increased LOS due to HAI caused by CR-PA (26.5 days) is longer than other MDRO infections (shorter than 19.8 days).