Review Article
TLR2 Arg753Gln Gene Polymorphism Associated with Tuberculosis Susceptibility: An Updated Meta-Analysis
Table 4
Subgroup analysis results of the association between TLR2 Arg753Gln gene polymorphism and TB risk in allele genetic models.
| | Variables | Subgroup | N | OR (95%CI) | P | I2 (%) |
| | Ethnicity | Caucasian | 9 | 2.62 (1.77, 3.87) | ≤0.01 | 33.6 | | Asian | 15 | 3.35 (2.37, 4.74) | ≤0.01 | 0.00 | | African | 2 | 2.08 (0.72, 6.03) | 0.18 | 0.00 | | Mixed | 3 | 0.76 (0.36, 1.64) | 0.49 | 62.9 | | HWE violation | Yes | 19 | 1.89 (1.26, 2.85) | ≤0.01 | 62.3 | | No | 10 | 3.30 (2.11, 5.17) | ≤0.01 | 0.00 | | Sample type | PB | 18 | 2.43 (1.66, 3.54) | ≤0.01 | 34.1 | | EPTB | 4 | 1.84 (0.83, 4.06) | 0.13 | 62.0 | | TB (PB+EPTB) | 7 | 1.84 (0.74, 4.59) | 0.19 | 62.2 |
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N: number; OR: odds ratio; CI: confidence interval.
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