Preoperative Management of MGD Alleviates the Aggravation of MGD and Dry Eye Induced by Cataract Surgery: A Prospective, Randomized Clinical Trial
Table 1
Outcomes of ocular surface and MGs parameters in Cohort I.
Parameters
Mean±SD
P-value
Baseline/Pre-op
1 month
3 months
Overrall
1M VS
3M VS
Baseline
Baseline
OSS
2.24±1.27
4.63±1.30
2.80±1.25
<0.001
<0.001
0.077
NIKBUT(s)
4.41±1.22
1.20±0.96
3.51±1.21
<0.001
<0.001
<0.001
Corneal FL
0.59±0.70
1.31±1.03
0.92±0.84
<0.001
<0.001
0.163
Schirmer(mm)
6.08±2.00
6.59±2.09
5.82±1.76
0.136
0.570
>0.999
Lid margin
2.47±0.50
3.25±0.72
2.76±0.81
<0.001
<0.001
0.099
Meibum quality
3.06±1.33
4.25±1.02
3.33±0.79
<0.001
<0.001
0.592
Expressibility
2.96±0.82
4.02±0.88
3.22±0.61
<0.001
<0.001
0.304
Meibography
2.63±0.70
2.71±0.64
2.67±0.68
0.841
>0.999
>0.999
Continuous values were analyzed by linear mixed model with Bonferroni post hoc analysis. Noncontinuous values were analyzed by generalized linear mixed model analysis with Bonferroni post hoc analysis. The investigative point of preoperation in Cohort I was the same point as the baseline (P < 0.001, P < 0.01, P < 0.05).
