Clinical Study

Preoperative Management of MGD Alleviates the Aggravation of MGD and Dry Eye Induced by Cataract Surgery: A Prospective, Randomized Clinical Trial

Table 3

Outcomes of ocular surface and MGs parameters in Cohort III.

ParametersMean±SDP-value
Baseline/Pre-op1 month3 monthsOverrall1M VS3M VS
BaselineBaseline

OSS2.36±1.453.82±1.332.54±1.00<0.001<0.001>0.999

NIKBUT(s)4.46±1.552.21±1.503.61±1.40<0.001<0.0010.101

Corneal FL0.68±0.721.07±0.860.75±0.650.1180.158>0.999

Schirmer(mm)6.57±2.176.14±1.826.46±1.480.665>0.999>0.999

Lid margin2.50±0.512.82±0.822.50±0.840.1770.321>0.999

Meibum quality3.14±1.273.68±1.023.21±0.740.1150.167>0.999

Expressibility2.82±0.863.43±0.842.93±0.900.0240.031>0.999

Meibography2.50±0.642.57±0.802.32±0.670.394>0.999>0.999

Continuous values were analyzed by linear mixed model with Bonferroni post hoc analysis. Noncontinuous values were analyzed by generalized linear mixed model analysis with Bonferroni post hoc analysis. The investigative point of preoperation in Cohort III was the same point as the baseline (P < 0.001, P < 0.01, P < 0.05).