Research Article
Overexpression of ICAM-1 Predicts Poor Survival in High-Grade Serous Ovarian Carcinoma: A Study Based on TCGA and GEO Databases and Tissue Microarray
Table 4
COX regression analysis of risk factors in patients with high-grade serous ovarian carcinoma.
| Characteristics | Univariate analysis | Multivariate analysis | HR (95%CI) | P | HR (95%CI) | P |
| ICAM-1 expression | | | | | Low expression | 1 | | 1 | | Overexpression | 4.924 (1.448,16.744) | 0.011 | 1.847 (0.331,10.322) | 0.484 | Age | | | | | >50 | 1 | | | | ≤50 | 0.939 (0.379,2.325) | 0.897 | | | Stage | | | | | Early (I-II) | 1 | | 1 | | Advanced (III-IV) | 11.296 (2.596,49.151) | 0.001 | 11.230 (1.090,115.705) | 0.042 | Ascites | | | | | No | 1 | | | | Yes | 1.094 (0.349,3.432) | 0.878 | | | Chemotherapy resistance | | | | | No | 1 | | 1 | | Yes | 3.587 (1.027,12.537) | 0.045 | 1.612 (0.482,5.387) | 0.438 |
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Abbreviations. HR: hazard ratio; CI: confidence interval.
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