Overexpression of ICAM-1 Predicts Poor Survival in High-Grade Serous Ovarian Carcinoma: A Study Based on TCGA and GEO Databases and Tissue Microarray

Table 4

COX regression analysis of risk factors in patients with high-grade serous ovarian carcinoma.

Characteristics	Univariate analysis		Multivariate analysis
	HR (95%CI)	P	HR (95%CI)	P
ICAM-1 expression
Low expression	1		1
Overexpression	4.924 (1.448,16.744)	0.011	1.847 (0.331,10.322)	0.484
Age
>50	1
≤50	0.939 (0.379,2.325)	0.897
Stage
Early (I-II)	1		1
Advanced (III-IV)	11.296 (2.596,49.151)	0.001	11.230 (1.090,115.705)	0.042
Ascites
No	1
Yes	1.094 (0.349,3.432)	0.878
Chemotherapy resistance
No	1		1
Yes	3.587 (1.027,12.537)	0.045	1.612 (0.482,5.387)	0.438

Abbreviations. HR: hazard ratio; CI: confidence interval.