Table 3: GO and KEGG pathway enrichment analysis of DEGs in the module. FDR<0.05 was considered statistically significant.

CategoryTermCountFDR

GOTERM_BPGO:0007204~positive regulation of cytosolic calcium ion concentration102.54E-10
GO:0007186~G-protein coupled receptor signaling pathway155.11E-09
GO:0007193~adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway69.72E-06
GO:0007218~neuropeptide signaling pathway64.76E-04
GO:0006954~inflammatory response70.0216325
GOTERM_CCGO:0005887~integral component of plasma membrane139.27E-05
GO:0005886~plasma membrane192.11E-04
GOTERM_MFGO:0042923~neuropeptide binding40.0035638
GO:0004930~G-protein coupled receptor activity80.0619499
KEGG_PATHWAYhsa04080:Neuroactive ligand-receptor interaction101.78E-05

GO, gene ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes; DEGs, differentially expressed genes; FDR, false discovery rate