Research Article

Feasibility and Health Effects of a 15-Week Combined Exercise Programme for Sedentary Elderly: A Randomised Controlled Trial

Table 3

Between-group difference after 15 weeks of training.

TG(n=30)CG(n=15)Between-Group
Difference
Change(95 CI)Change(95 CI)(95 CI) P- Value

Body composition
Weight (kg)-1.1(-2.0 to -0.2)1.3(-0.0 to 2.6)-2.3(-4.0 to -0.7)0.006
Body Mass Index (kg/m2)-0.5(-0.8 to -0.1)0.4(-0.1 to 0.8)-0.8(-1.4 to -0.3)0.004
Total muscle mass (kg)0.4(0.0 to 0.9)0.5(-0.2 to 1.2)0.0(-0.9 to 0.9)0.974
Total fat percentage (%)-1.4(-2.1 to -0.7)0.2(-0.8 to 1.2)-1.6(-2.8 to -0.3)0.014
Total fat mass (kg)-1.4(-2.2 to -0.5)0.6(-0.6 to 1.9)-2.0(-3.5 to -0.5)0.010
Android fat mass (kg)-0.2(-0.3 to -0.1)0.1(-0.1 to 0.2)-0.3(-0.4 to -0.1)0.003
Gynoid fat mass (kg)-0.3(-0.4 to -0.2)0.0(-0.2 to 0.3)-0.3(-0.6 to -0.1)0.010
Total bone mineral density (g/cm2)0.000(-0.001 to 0.011)0.012(0.003 to 0.021)-0.007(-0.018 to 0.004)0.220
Total bone mineral content (kg)-0.004(-0.068 to -0.012)-0.030(-0.071 to 0.010)-0.009(-0.060 to 0.042)0.712
Aerobic Fitness
(mLO2/min)15.5(-75.3 to 106.4)84.9(-58.8 to 228.7)-69.4(-244.3 to 105.5)0.423
(mL/min/kg)0.7(-0.4 to 1.8)0.4(-1.3 to 2.1)0.3(-1.8 to 2.3)0.790
Resting heart rate (bpm)1(-1 to 3)1(-2 to 4)0(-3 to 4)0.895
Blood pressure
Systolic blood pressure (mmHg)-5(-9 to -1)-4(-10 to 2)-1(-9 to 7)0.752
Diastolic blood pressure (mmHg)-4(-6 to -1)-2(-5 to 1)-1(-5 to 3)0.522
Mean arterial blood pressure (mmHg)-4(-7 to -1)-3(-7 to 1)-1(-6 to 4)0.597
Lipids
Total Cholesterol (mmol/L)-0.2(-0.4 to 0.1)0.1(-0.3 to 0.5)-0.3(-0.7 to 0.2)0.254
HDL-Cholesterol (mmol/L)0.0(-0.1 to 0.1)0.1(0.0 to 0.2)-0.1(-0.2 to 0.0)0.165
LDL-Cholesterol (mmol/L)0.0(-0.2 to 0.3)0.3(0.0 to 0.6)-0.2(-0.6 to 0.2)0.264
Triglyceride (mmol/L)-0.2(-0.3 to 0.0)-0.2(-0.4 to 0.0)0.0(-0.3 to 0.3)0.919
Total Chol/HDL ratio-0.2(-0.4 to 0.1)0.0(-0.3 to 0.3-0.2(-0.6 to 0.2)0.404
Glycemic control
Fasting insulin (pmol/L)-27.7(-38.4 to -17.0)-34.5(-49.1 to -19.9)6.8(-11.4 to 25.0)0.451
HbA1c %0.1(0.0 to 0.1)0.0(0.0 to 0.1)0.0(-0.1 to 0.1)0.810

CRP (mg/L)-0.4(-1.2 to 0.3)-0.6(-1.6 to 0.4)0.2(-1.1 to 1.4)0.794
eAG (mmol/L)0.1(0.0 to 0.2)0.1(0.0 to 0.2)0.0(-0.1 to 0.2)0.669
Bone markers
Osteocalcin (µg/L)1.5(-0.4 to 3.5)0.1(-2.5 to 2.7)1.4(-1.8 to 4.7)0.379
P1NP (µg/L)11.5(5.1 to 18.0)1.4(-7.2 to 10.0)10.1(-0.7 to 20.9)0.066
CTX-1 (µg/L)-0.0(-0.1 to 0.1)0.0(-0.1 to 0.1)0.0(-0.1 to 0.1)0.705
Sclerostin (ng/mL)0.05(-0.0 to 0.1)0.03(-0.1 to 0.1)0.02(-0.1 to 0.1)0.696

TG: training group. CG: control group. Within-group data are presented as mean change (95% CI) and between-group data as estimated mean difference (95% CI). denotes significant between-group effect (P<0.05)    (P<0.01).