BioMed Research International / 2019 / Article / Tab 4

Research Article

α-1-Acid Glycoprotein Concentration as an Outcome Predictor in Adult Patients with Sepsis

Table 4

Association between AGP levels and other manifestations in patients with sepsis (survivors and non-survivors).

SurvivorsNon-survivorsCrude ORp valueAdjusted ORp value
n=68n=19(95% CI)(95% CI)

Age (y) (mean ± SD)64.0 ± 15.469.5 ± 12.30.16
Male/Female (n)45/2314/51.43 (0.46-4.47)0.59
Potential diseases [n (%)]
 Diabetes19 (27.9)9 (47.4)2.32 (0.82-6.60)0.16
 Hypertension36 (52.9)9 (47.4)0.80 (0.29-2.22)0.80
 Chronic lung disease7 (10.3)2 (10.5)1.02 (0.20-5.40)1.00
 Cerebrovascular disease9 (13.2)3 (15.8)1.23 (0.30-5.08)1.00
 Chronic heart disease3 (4.4)2 (10.5)2.55 (0.39-16.5)0.64
 Chronic renal disease15 (22.1)7 (36.8)2.06 (0.69-6.16)0.24
Clinical presentations (mean ± SD)
 Systolic BP (mmHg)95.3 ± 33.896.8 ± 35.90.87
 Heart rate (bpm)109.2 ± 25.5114.0 ± 28.30.48
Shock within 24 hours [n (%)]53 (77.9)18 (94.7)5.09 (0.63-41.3)0.18
Clinical severity index (mean ± SD)
 Maximum 24-h APACHE II score19.1 ± 6.723.5 ± 9.10.021.13 (1.01-1.26)0.04
Bacteremia [n (%)]27 (39.7)6 (31.6)1.15 (0.24-2.01)0.70
Intervention within 24 hours [n (%)]
 Mechanical ventilator18 (26.5)12 (63.2)4.76 (1.62-13.9)0.01
 Vasoactive agent5 (71.4)1 (14.3)0.07 (0.01-0.97)0.10
Laboratory data (mean ± SD)
White blood cells (×109/L)13.5 ± 7.517.9 ± 8.6<0.05
Hemoglobin (mg/dL)11.9 ± 2.011.9 ± 2.80.98
Platelet counts (×104/L)182.6 ± 109.6159.5 ± 84.00.40
C-reactive protein (mg/L)156.9 ± 110.0216.8 ± 89.60.02
Lactate (mg/dL)29.1 ± 10.339.1 ± 13.2<0.011.105 (1.02-1.2)0.01
Cr (mg/dL)2.1 ± 1.62.6 ± 2.40.28
GOT (mg/dL)57.01 ± 41.860.6 ± 49.60.77
Procacitonin (mg/dL)24.0 ± 26.7.28.4 ± 32.20.67
AGP (ng/ml)1039.0 ± 321.81491.8 ± 449.2<0.011.005 (1.002-1.008)<0.01

SD, standard deviation; APACHE, Acute Physiology and Chronic Health Evaluation

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