1 capsule per day (112.5 × 109 CFU per capsule); 1 OFA capsule per day (180 mg EPA, and 120 mg DHA)
VSL#3 alone or in combination of OFA supplementation: ↓ Total cholesterol, triglyceride, LDL, VLDL, and hsCRP ↑ HDL level, insulin sensitivity. Altered the gut microbiota positively. OFA supplementation did not affect the microbiota.
The combination of VSL#3 and OFA showed more pronounced effects.
Preobese-obese, normal weight obese, and normal weight lean women
Psychobiotics (B. bifidum SGB02, B. animalis subsp. lactis SGB06, Streptococcus thermophilus SGSt01, S. thermophiles, L. plantarum SGL07, L. delbrueckii spp. bulgaricus DSM 20081, L. reuteri SGL01, L. acidophilus SGL11, Lactococcus lactis subsp. lactis SGLc01)
Each 1.5 ×1010 CFU per day
↓ BMI, Fat mass ↓ Psychopathological scores ↓ Bacterial overgrowth syndrome ↓ BUT_GSI scale ↑ Free fat mass Improved the meteorism and defecation frequency
Psychobiotics supplementation improved the body composition, reduced the dysbiosis, and reduced the psychopathological scores in preobese-obese and normal weight obese people.
Familact® L. casei (3.5 × 109 CFU), L. rhamnosus (7.5 × 108 CFU), L. bulgaricus (108 CFU), L. acidophilus (109 CFU), B. breve (1010 CFU), B. longum (3.5 × 109 CFU), and S. thermophilus (108 CFU), and fructo-oligosaccharide (38.5 mg) in one sachet
One sachet per day
4 weeks before surgery and 12 weeks after surgery
Improved the vitamin D status, inflammatory markers, lipid profile, and glycemic indices. No changes in folate, vitamin B12, and homocysteine levels
Familact® supplementation improved inflammatory markers and promoted weight loss in OAGB-MGB patients.
Intervention starts from 14-20 weeks of the gestation and continued until delivery of the baby; ↓: Reduced; BMI: Body mass index; BP: Blood pressure; VSL#3: A probiotic formulation containing three strains of Bifidobacterium and four strains of Lactobacillus; EPA: Eicosapentaenoic acid; DHA: Docosahexaenoic acid; TG: Triglyceride; LDL: Low-density lipids; VLDL: Very-low-density lipids; HDL: High-density lipids; hsCRP: High-sensitivity C-reactive protein; Vivomixx®: A probiotic formulation containing eight bacterial strains; AAT: Alanine aminotransferase; AsAT: Aspartate aminotransferase; BUT_GSI scale: Body uneasiness test and global severity index; OAGB-MGB: Anastomosis Gastric Bypass-Mini Gastric Bypass; QUICKI: Quantitative Insulin Sensitivity Check Index; HOMA-IR: Homoeostasis Model of Assessment-Insulin Resistance; LPS: Lipopolysaccharide.