FcgRIII Deficiency and FcgRIIb Deficiency Promote Renal Injury in Diabetic Mice

Table 1

General and biochemical parameters of diabetic, high-fat, and nondiabetic control mice.

Mice	WT			FcgRIIb-/-			FcgRIII-/-
	Control	HFD	DM	WT	HFD	DM	Control	HFD	DM
Blood glucose (mmol/l)	9.7±0.54	14.8±0.4	26.7±0.79	8.1±0.27	11.3±0.27	27.4±0.92	7±0.31	17.7±0.45	30.4±0.58
body weight (g)	24.6±0.38	32.9±0.78	27.7±0.51	24.3±0.47	37.73±0.56	30.5±0.78	26.3±0.27	41±1.1	33.5±0.51
Serum creatinine (umol/l)	10.67±0.44	15.97±0.53	23.81±0.95	11.1±0.52	16.02±0.59	26.7±0.39	13±0.43	17.28±0.61	27.±0.71
BUN (mmol/l)	5.9±0.39	8.36±0.20	9.74±0.12	6.60±0.36	7.60±0.19	11.13±0.25	6.54±0.13	8.79±0.14	11..51±0.18
LDL (mmol/l)	0.16±0.01	0.59±0.08	0.52±0.04	0.25±0.01	0.65±0.07	0.71±0.02	0.25±0.02	0.72±0.06	0.71±0.03
Chol (mmol/l)	2.01±0.08	4.41±0.08	4.17±0.16	2.16±0.09	5.58±0.18	5.26±0.18	2.20±0.38	5.68±0.07	5.15±0.13

Data are expressed as the mean ± SEM.
p<0.05 versus respective nondiabetic control.
p<0.05 versus respective HFD control.
p<0.05 versus WT with DM.