Comparison of Preoperative Neutrophil-Lymphocyte and Platelet-Lymphocyte Ratios in Bladder Cancer Patients Undergoing Radical Cystectomy

Table 3

Univariate and multivariate analyses of factors associated with CSS in bladder cancer patients undergoing radical cystectomy.

Variable	Univariate		Multivariate
	HR (95% CI range)	value	HR (95% CI range)	value
Age	1.023 (1.001–1.046)	0.046
Gender	0.977 (0.484–1.971)	0.948
CCI	1.120 (0.865–1.451)	0.391
Grade	1.990 (0.622–6.361)	0.246
LVI	0.454 (0.277–0.743)	0.002
Adjuvant chemotherapy	1.569 (0.884–2.786)	0.124
Hydronephrosis	2.993 (1.854–4.832)	<0.001
T stage	1.949 (1.571–2.416)	<0.001	1.761 (1.336–2.321)	<0.001
N stage	4.187 (2.480–7.069)	<0.001	2.855 (1.401–5.819)	0.004
NLR	1.656 (1.020–2.687)	0.041
PLR	2.083 (1.283–3.381)	0.003	1.761 (1.336–2.321)	0.039

HR: hazard ratio; CCI: Charlson comorbidity index; LVI: lymphovascular invasion; CIS: carcinoma in situ; NLR: neutrophil-to-lymphocyte ratio; PLR: platelet-to-lymphocyte ratio.