Noninvasive Indirect Markers of Liver Fibrosis in Alcoholics

Table 2

The values of noninvasive markers in patients with significant, no significant fibrosis, without and with cirrhosis.

Fibrosis; Markers	No significant fibrosis; (F0-F1, F1, F1-F2); (n=51)	Significant fibrosis; (F≥2); (n=21)	Without cirrhosis; (F0-F1, F1, F1-; F2, F2, F3); (n=76)	Cirrhosis; (F3-F4, F4); (n=14)
APRI	1.72 ± 1.73	2.18 ± 2.21	1.80 ± 1.74	4.02 ± 2.84
		P1=0.254		P2=0.001
Forn’s	8.85 ± 1.79	9.83 ±1.83	9.12 ± 1.92	11.71 ± 1.77
		P1=0.063		P2<0.001
FIB-4	4.21 ± 3.37	6.47 ± 6.23	4.64 ± 4.01	10.77 ± 5.50
		P1=0.131		P2<0.001
GAPRI	158 ± 219	295 ± 300	276 ± 287	832 ± 652
		P1=0.020		P2<0.001
AP	4.74 ± 2.27	5.57 ± 2.13	4.91 ± 2.23	6.86 ± 2.28
		P1=-1.003		P2=0.004
Hepascore	0.39 ± 0.21	0.60 ± 0.28	0.43 ± 0.25	0.80 ± 0.21
		P1=0.008		P2<0.001
FibroTest	0.32 ± 0.08	0.58 ± 0.08	0.38 ± 0.14	0.87 ± 0.09
		P1<0.001		P2<0.001

Data are presented as mean ± SD. P1: P value between significant and no significant fibrosis; P2: P value between cirrhosis and no cirrhosis; means statistically significant difference.