Research Article

Technical Verification and Assessment of Independent Validation of Biomarker Models for Endometriosis

Table 5

Coefficients and model performance of diagnostic models for endometriosis that were newly developed in patients who did not use hormonal medication in the technical verification and the validation study.

VariableModel coefficientP-valueModelC-indexN patients
P-value(95% CI)

Technical verification study all phases combined all endometriosis

Intercept0.82880.05810.00450.685 (0.590;0.780)136
CA-1250.03780.0326
Annexin V-0.03870.0261

Validation study all phases combined all endometriosis

Intercept-0.13200.63320.00020.733 (0.661;0.805)198
CA-1250.03420.0070

Validation study all phases combined US-neg endometriosis

Intercept1.47930.07970.00230.698 (0.617;0.778)162
CA-1250.02770.0328
sICAM-1-0.00860.0314