Naringin Reverses High-Cholesterol Diet-Induced Vascular Dysfunction and Oxidative Stress in Rats via Regulating LOX-1 and NADPH Oxidase Subunit Expression

Table 2

A comparison of the sensitivity (pEC50) and maximum relaxation (R_max) response to ACh and SNP in aortic rings from control and hypercholesterolaemic rats with or without naringin treatment for 4 weeks.

	ACh		SNP
	pEC50	Rmax	pEC50	Rmax
C	7.32 ± 0.07	99 ± 1	8.50 ± 0.17	100 ± 0
HC	6.60 ± 0.07	65 ± 5	8.12 ± 0.13	100 ± 0
HCN	7.37 ± 0.10^###	97 ± 1^###	8.54 ± 0.24	100 ± 0
CN	7.13 ± 0.17^##	96 ± 4^###	8.46 ± 0.10	100 ± 0

Results are shown as the mean ± SEM. n = 8–10 rats. vs. C group; , vs. HC group.