Effects of Cervical Rotatory Manipulation (CRM) on Carotid Atherosclerosis Plaque in Vulnerability: A Histological and Immunohistochemical Study Using Animal Model

Figure 5

Immunohistochemistry of CAS in the CAS-CRM group (n=8) and the CAS group (n=10). (a) CD34 staining in the CAS-CRM group, micro-vessel with brown stained (×200) (red arrow). (b) CD34 staining in the CAS group (×200). (c) CD68 staining in the CAS-CRM group, macrophages with brown stained (×200) (blue arrow). (d) CD68 staining in the CAS group (×200). (e) Difference in MVD and IOD in plaque between the CAS-CRM and the CAS groups. P<0.05; CAS, carotid atherosclerosis; CRM, cervical rotatory manipulation; MVD, mean micro-vessel density; IOD, integrated optimistic density.

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