Antimicrobial Activity of 4-Chlorocinnamic Acid Derivatives

Table 1

Minimum inhibitory concentration MIC (μmol/mL) of compounds 1-12 against yeasts of the Candida genus, Microdilution Technique.

Compounds	Candida albicans	Candida glabrata	Candida krusei	Candida guilliermondii
	ATCC 90028	ATCC 90030	ATCC 34135	ATCC 22017
1	5.09 μmol/mL	5.09 μmol/mL	+	1.27 μmol/mL
2	4.75 μmol/mL	4.75 μmol/mL	4.75 μmol/mL	1.19 μmol/mL
3	+	+	+	2.22 μmol/mL
4	+	+	+	2.22 μmol/mL
5	+	4.19 μmol/mL	+	2.09 μmol/mL
6	2.08 μmol/mL	2.08 μmol/mL	4.16 μmol/mL	0.13 μmol/mL
7	+	3.96 μmol/mL	+	1.98 μmol/mL
8	3.10 μmol/mL	3.10 μmol/mL	3.10 μmol/mL	1.55 μmol/mL
9	+	+	+	0.40 μmol/mL
10	+	+	+	0.41 μmol/mL
11	1.58 μmol/mL	1.58 μmol/mL	0.78 μmol/mL	0.024 μmol/mL
12	2.85 μmol/mL	2.85 μmol/mL	2.85 μmol/mL	1.42 μmol/mL
Control of the environment	-	-	-	-
Nystatin	0.00043 μmol/mL	0.00043 μmol/mL	0.00043 μmol/mL	0.00043μmol/mL
Control of the microorganism	+	+	+	+

(+) indicates growth of the microorganism; (-) no growth microorganism.