Quantitative Proteomic Analyses of a Pathogenic Strain and Its Highly Passaged Attenuated Strain of Mycoplasma hyopneumoniae

Table 4

VirulentPred screening of the 35 overrepresented proteins in M. hyopneumoniae 168. References supporting the association with virulence are included.

Identified Proteins	Accession Number	Prediction results	Reference
Putative uncharacterized protein	ADQ90691	Virulent	Okan et al. 2013; Shahbaaz et al. 2015
Hypothetical protein	ADQ90530	Virulent	Cheng et al. 2017
Putative uncharacterized protein	ADQ90824	Virulent	Heithoff et al. 1999; Shahbaaz et al. 2015
Putative uncharacterized protein	ADQ90745	Virulent	Gay et al. 1991; Kobe et al. 2001
Cysteinyl-tRNA synthetase	ADQ90838	Virulent
Putative uncharacterized protein	ADQ90859	Virulent	Cheng et al. 1996; Monnerat et al. 1999
Pts system, lichenan-specific IIa component	ADQ90264	Virulent
ABC transporter ATP-binding-Pr1	ADQ90875	Virulent	Garmory et al. 2004
Hypothetical protein	ADQ90910	Virulent	Twine et al. 2006
ABC transporter protein	ADQ90806	Virulent	Garmory et al. 2004
Sugar ABC transporter ATP-binding protein	ADQ90805	Virulent	Garmory et al. 2004
MG2+ ion transporter	ADQ90693	Virulent	Groisman et al. 2013; Merino et al. 2001; O'Connor et al. 2009
Ribonuclease III	ADQ90602	Virulent	Haddad et al. 2013; Mao et al. 2016
Ribose-phosphate pyrophosphokinase	ADQ90852	Virulent	Donini et al. 2017
Putative uncharacterized protein	ADQ90827	Virulent
Hypothetical protein	ADQ90324	Virulent
Lipoprotein	ADQ90620	Virulent
PTS system galactitol-specific enzyme IIB component	ADQ90760	Virulent
Enolase	ADQ90480	Nonvirulent	Bao et al. 2014; Pancholi 2001; Schreiner et al. 2012
Translation elongation factor Tu	ADQ90729	Nonvirulent	Dallo et al. 2002; Jiang et al. 2016
Cation-transporting P-type ATPase	ADQ90498	Nonvirulent	Novoa-Aponte et al. 2014
Probable O-sialoglycoprotein endopeptidase	ADQ90833	Nonvirulent	Aruni et al. 2011; Davis et al. 2003
Lipoate-protein ligase A	ADQ90531	Nonvirulent	O'Riordan et al. 2003
Lipoate-protein ligase A	ADQ90484	Nonvirulent	O'Riordan et al. 2003
Endo-1,4-beta-glucanase	ADQ90389	Nonvirulent	Robinson et al. 2013
Acetate kinase AckA	ADQ90711	Nonvirulent
NADH dependent flavin oxidoreductase	ADQ90532	Nonvirulent
Glycerol transporter subunit A	ADQ90619	Nonvirulent
Glycerol kinase	ADQ90587	Nonvirulent
Triacylglycerol lipase	ADQ90483	Nonvirulent
Hypoxanthine phosphoribosyltransferase	ADQ90492	Nonvirulent
Transport protein sgaT	ADQ90622	Nonvirulent
CTP synthase	ADQ90509	Nonvirulent
Thymidine kinase	ADQ90808	Nonvirulent
Purine-nucleoside phosphorylase	ADQ90309	Nonvirulent