A Six-Gene Signature Predicts Survival of Adenocarcinoma Type of Non-Small-Cell Lung Cancer Patients: A Comprehensive Study Based on Integrated Analysis and Weighted Gene Coexpression Network

Figure 3

Identification of consensus DEGs in the training and the test datasets of NSCLC patients. (a) Heat map and two-way hierarchical clustering based on 7076 DEGs that were differentially expressed between NSCLC and ANT samples of the training set. ANT (green label) and NSCLC (red label) samples fell into separate clusters. (b) The 3592 DEGs NSCLC (red label) vs. ANT (blue label) of the TCGA-LUAD test set. Each column represents a sample, and each row represents the mRNA level. The color scale represents the raw Z-score ranging from blue (low expression) to red (high expression). Dendrograms beside each heat map correspond to the hierarchical clustering of the 3592 DEGs by the expression level. (c) A Venn diagram showing the overlap of DEGs detected in the training and test sets. Figure 3 was reproduced from Sun et al. [16].

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