A Six-Gene Signature Predicts Survival of Adenocarcinoma Type of Non-Small-Cell Lung Cancer Patients: A Comprehensive Study Based on Integrated Analysis and Weighted Gene Coexpression Network

Figure 6

The prognostic performance of the six-gene signature in the TCGA-LUAD test cohort. (a) Risk score analysis of the six-gene signature of NSCLC. Risk score of gene signature (top); duration of cases (middle); low and high score groups for the six genes (bottom). (b) Survival analysis of the high-risk group and the low-risk group using Kaplan–Meier curves. (c) The prognostic efficiency of the six-gene signature for survival time. ROC curves of the six-gene signature for predicting 1- to 10-year survival were analyzed. (d–i) The independent prognostic efficiency of individual mRNA in the six-gene signature of the test set. (d) RRM2; (e) RPS6KL1; (f) RTL1; (g) RXFP1; (h) RRAGB; (i) RSPH9. Horizontal axis, overall survival time. Vertical axis, overall survival.

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