A Six-Gene Signature Predicts Survival of Adenocarcinoma Type of Non-Small-Cell Lung Cancer Patients: A Comprehensive Study Based on Integrated Analysis and Weighted Gene Coexpression Network

Table 1

Characteristics of the public microarray datasets used in this study.

Study	Species/array platform	Samples	Number of samples	Set
GSE19188	[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array(GPL570)	NSCLC vs. control tissue	NSCLC = 91 (LUAD 45, LUSC 46), control tissue = 65, total = 156	Training set
GSE30219	[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array(GPL570)	NSCLC vs. control tissue	NSCLC = 293, control tissue = 14, total = 307	Training set
GSE10072	[HG-U133A] Affymetrix Human Genome U133A Array (GPL96)	NSCLC vs. control tissue	NSCLC = 58 (LUAD 58), control tissue = 49, total = 107	Training set
GSE7670	[HG-U133A] Affymetrix Human Genome U133A Array (GPL96)	NSCLC vs. control tissue	NSCLC = 28 (LUAD 28), control tissue = 30, total = 58	Training set
GSE2514	[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array (GPL81)	NSCLC vs. control tissue	NSCLC = 20, control tissue = 19, total = 39	Training set
GSE32863	Illumina HumanWG-6 v3.0 expression beadchip (GPL6884)	NSCLC vs. control tissue	NSCLC = 58 (LUAD 58), control tissue = 58, total = 116	Training set
GSE21933	Phalanx Human OneArray (GPL6254)	NSCLC vs. control tissue	NSCLC = 21, control tissue = 21, total = 42	Training set
GSE40275	Human Exon 1.0 ST Array (GPL15974)	NSCLC vs. control tissue	NSCLC = 41, control tissue = 43, total = 84	Training set
GSE12472	Agilent-012391 Whole Human Genome Oligo Microarray G4112A (Feature Number version) (GPL1708)	NSCLC vs. control tissue	NSCLC = 35 (LUSC 35), control tissue = 28, total = 63	Training set
GSE80796	[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] (GPL6244)	NSCLC vs. control tissue	NSCLC = 309, control tissue = 196, total = 505	Training set
GSE8500	Human 3.0 A1 (GPL3991)	NSCLC vs. control tissue	NSCLC = 40, control tissue = 8, total = 48	Training set
GSE85841	Agilent-067406 Human CBC lncRNA + mRNA microarray V4.0 (GPL20115)	NSCLC vs. control tissue	NSCLC = 8, control tissue = 8, total = 16	Training set
GSE19027	[HG-U133A] Affymetrix Human Genome U133A Array (GPL96)	NSCLC vs. control tissue	NSCLC = 21, control tissue = 39, total = 60	Training set
TCGA-LUAD	Human Illumina HiSeq 2000	LUAD vs. control tissue	LUAD = 517, control tissue = 59, total = 576	Test set
GSE11969	Agilent Homo sapiens 21.6 K custom array (GPL7015)	Overall survival	LUAD = 94, Overall survival information = 94	Validation set

GSE, Gene Expression Omnibus accession number; TCGA, the Cancer Genome Atlas; NSCLC, non-small-cell lung cancer; LUAD, lung adenocarcinomal; LUSC, lung squamous cell carcinoma.