Unique Roles of Sphingolipids in Selected Malignant and Nonmalignant Lesions of Female Reproductive System

Figure 1

Metabolism of sphingolipids: serine palmitoyl transferase (SPT), (dihydro)ceramide synthase(CERS), dihydroceramide desaturase (DES), diacylglycerol (DAG), sphingomyelinases (SMase), SM synthase (SMS), glucosylceramide (GlcCER), glucosylceramide synthase (GCS), ceramide-1-phosphate (Cer-1-P), ceramide kinase (CK), ceramidases (CDases), sphingosine kinase (SK), cerebrosidase (CRS), and phosphatases of CER-1-P and S1P (C1PP and S1PP).