BioMed Research International / 2019 / Article / Fig 3

Research Article

Arsenic Trioxide Suppresses Tumor Growth through Antiangiogenesis via Notch Signaling Blockade in Small-Cell Lung Cancer

Figure 3

Transfection of Dll4 overexpression lentiviruses and Notch1 siRNA lentiviruses into HUVECs. The morphology (upper panels) and green fluorescence expression (lower panels) of HUVECs with or without transfection of Dll4 overexpression (a) or siNotch1 lentiviruses (b). (c) Transfection of Dll4 overexpression lentiviruses resulted in an increase in Dll4 mRNA level in HUVECs. (d) Transfection of Notch1 siRNA lentiviruses reduced the Notch1 mRNA level in HUVECs. (e) Transfection of Dll4 overexpression lentiviruses upregulated Dll4 protein level in HUVECs. (f) Transfection of Notch1 siRNA lentiviruses reduced Notch1 protein level in HUVECs. Columns, mean; error bars, SD. , .

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