Review Article
Potential Role of Exosomes in Cancer Metastasis
Table 3
Potential exosomal biomarkers of cancer metastasis.
| ā | Potential biomarkers | Comparison analysis | Ref. |
| Exosomal RNAs | miR-140-3p, miR-30d-5p, miR-29b-3p, miR-130b-3p, miR-330-5p, miR-296-3p | Exosomes derived from fast- and slow-migrating groups of PDLCs | [41] | miRNA-21 and lncRNA-ATB | Serum exosomes isolated from patients with different HCC stages | [42] | miR-9 and miR-155 | Exosomes derived from breast cells with different metastatic ability | [43] | miR-1290 and miR-375 | Plasma exosomes derived from CRPC patients with different prognosis | [44] | miR-130b and Met | Serum exosomes isolated from prostate cancer patients and healthy donors | [45] | circPRMT5 | Serum and urine exosomes from normal people and patients with UCB | [46] |
| Exosomal proteins | CD82 | Exosomes derived from tissue, serum, and plasma in breast cancer patients | [47] | Eps8 | Exosomes purified from human pancreatic cancer cell lines with distinct stages | [48] | CXCR7 and CXCL12 | Exosomes isolated from tissues of primary tumor, lung metastasis, and benign lung disease in CRC patients | [49] |
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Note: Patient-derived liver cell, PDLC; Hepatocellular carcinoma, HCC; Castration-resistant prostate cancer, CRPC; Urothelial carcinoma of the bladder, UCB; Colorectal cancer, CRC.
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