Research Article

Interleukin-6 and Interleukin-15 as Possible Biomarkers of the Risk of Autoimmune Diabetes Development

Table 3

Clinical and biochemical characteristics of the first-degree relatives’ subgroups.

Ab (+) first-degree relatives (FDR)Ab (−) first-degree relatives (FDR) value

N3139
Age (years)32.0 (18–60)31.0 (18–60)0.4
BMI (kg/m2)22.4 (17.0–37.5)21.9 (18–36.4)0.2
GADA (U/ml)0.9 (0.7–218.7)0.7 (0.6–0.9)0.01
IAA (U/ml)8.2 (4.4–13.2)6.7 (0.8–8.7)<0.001
IA-2A (U/ml)0.6 (0.6–0.9)0.6 (0.6–0.7)0.6
eGDR (mg/kg/min)11.5 (7.0–13.9)11.4 (7.0–12.8)1.0
HOMAIR3.9 (0.5–7.3)2.1 (0.2–8.8)0.02
IL-15 (pg/ml)1.7 (0.8–7.2)0.2 (0.2–0.6)<0.001
IL-6 (pg/ml)1.4 (0.3–4.6)0.3 (0.1–1.3)<0.001

Data are shown as medians (interquartile range).