Research Article
Interleukin-6 and Interleukin-15 as Possible Biomarkers of the Risk of Autoimmune Diabetes Development
Table 3
Clinical and biochemical characteristics of the first-degree relatives’ subgroups.
| | Ab (+) first-degree relatives (FDR) | Ab (−) first-degree relatives (FDR) | value |
| N | 31 | 39 | | Age (years) | 32.0 (18–60) | 31.0 (18–60) | 0.4 | BMI (kg/m2) | 22.4 (17.0–37.5) | 21.9 (18–36.4) | 0.2 | GADA (U/ml) | 0.9 (0.7–218.7) | 0.7 (0.6–0.9) | 0.01 | IAA (U/ml) | 8.2 (4.4–13.2) | 6.7 (0.8–8.7) | <0.001 | IA-2A (U/ml) | 0.6 (0.6–0.9) | 0.6 (0.6–0.7) | 0.6 | eGDR (mg/kg/min) | 11.5 (7.0–13.9) | 11.4 (7.0–12.8) | 1.0 | HOMAIR | 3.9 (0.5–7.3) | 2.1 (0.2–8.8) | 0.02 | IL-15 (pg/ml) | 1.7 (0.8–7.2) | 0.2 (0.2–0.6) | <0.001 | IL-6 (pg/ml) | 1.4 (0.3–4.6) | 0.3 (0.1–1.3) | <0.001 |
|
|
Data are shown as medians (interquartile range).
|