Biochemical Changes in Blood of Patients with Duchenne Muscular Dystrophy Treated with Granulocyte-Colony Stimulating Factor

Table 5

The aminotransferases activity and the cholesterol level in children and adolescents with Duchenne muscular dystrophy in each cycle of treatment with granulocyte-colony stimulating factor.

Measurement		AST (44 U/l)			ALT (37 U/l)			Cholesterol (120-200 mg/dl)
		Average	SD	P value	Average	SD	P value	Average	SD	P value
Cycle 1	1	215.05	114.05	0.001	224.63	132.88	0.011	172.21	38.50	<0.001
	2	144.11	87.13		195.37	112.73		143.65	30.81
Cycle 2	1	147.06	65.28	0.001	174.47	101.43	NS	176.24	26.53	<0.001
	2	115.35	58.54		166.76	111.36		150.32	29.04
Cycle 3	1	175.63	110.13	0.001	209.63	133.61	0.006	171.13	38.92	<0.001
	2	110.53	54.54		178.63	123.28		136.40	36.70
Cycle 4	1	181.16	162.31	NS	224.42	149.88	NS	168.10	33.32	<0.001
	2	120.47	87.66		193.00	118.18		140.61	33.30
Cycle 5	1	168.40	150.10	0.023	187.00	141.25	NS	164.62	33.84	<0.001
	2	99.33	65.91		167.93	130.43		142.83	35.40

AST, aspartate transaminase; ALT, alanine transaminase; NS, nonsignificant.