Xin-Ji-Er-Kang Alleviates Myocardial Infarction-Induced Cardiovascular Remodeling in Rats by Inhibiting Endothelial Dysfunction

Table 2

Effects of XJEK on cardiac function injury in MI rats.

Group	Time	HR; (Times/min)	ASBP; (mmHg)	LVEDP; (mmHg)	LVSP; (mmHg)	+dp/dtmax; (mmHg/s)	-dp/dtmax; (mmHg/s)
Control	0wk	381.63±33.58	96.67±2.92	-16.42±3.88	109.51±2.83	4049.67±237.23	-3317.31±183.80
Sham	2wk	403.14±38.88	95.31±3.76	-23.47±3.79	119.82±3.06	3972.84±122.19	-3546.74±220.85
MI		450.00±32.07	109.80±4.06	-8.92±4.57	126.38±4.20	4572.79±227.81	-4031.96±183.64
MI+XJEK		376.86±42.73	92.97±3.94^##	-15.67±8.09	109.07±4.78^#	3687.44±228.53^#	-3302.12±262.12^#
MI+Fosinopril		400.38±23.00	93.83±3.86^#	-14.69±2.89	102.89±5.34^##	3246.49±198.24^###	-3012.45±329.80^#
Sham	4wk	372.64±12.31	91.64±1.64	-27.43±1.79	113.58±3.46	3749.03±212.07	-3390.87±201.06
MI		428.00±50.08	110.92±4.63	-9.21±4.25	135.18±4.73	4541.46±308.14	-4292.16±757.17
MI+XJEK		399.50±18.09	90.34±2.57^###	-20.65±1.90	107.83±3.67^##	3402.62±130.43^##	-2983.99±139.16^##
MI+Fosinopril		386.40±41.21	92.41±2.85^##	-20.53±1.37^#	106.28±11.90^##	3402.17±235.64^##	-3305.10±383.84^##
Sham	6wk	387.30±18.66	103.51±4.83	-28.18±2.69	119.76±7.11	4279.16±402.39	-3694.09±289.27
MI		402.50±17.21	90.91±4.48	-7.26±7.39	107.51±6.02	3445.35±416.49	-2870.24±244.74
MI+XJEK		389.33±10.04	113.42±4.32^##	-22.98±1.98^#	129.06±4.97^#	4876.77±369.09^#	-4270.13±210.55^##
MI+Fosinopril		385.82±28.82	115.23±2.72^##	-23.84±1.77^#	128.82±11.65^##	4937.62±203.45^##	-4117.43±228.77^##

Data are represented as mean±SEM (n=8~10). <0.05, <0.01, and <0.001versus sham group; ^#P<0.05, ^##P<0.01, and ^###P<0.001 versus MI group.