Efficacy of Artesunate against Pseudomonas aeruginosa Biofilm Mediated by Iron

Figure 6

(a) Confocal laser scanning images. Three days later, the biofilm was exposed to different concentrations of artesunate (AS) combine ferrous iron for 12 h (A) Control, (B) 512 μg/ml AS, (C) 1024 μg/ml AS, (D) 512 μg/ml AS + Fe, (E) 1024 μg/ml AS + Fe(II). (b) COMSTAT analysis of biofilms parameters. Three days later, the biofilm was exposed to different concentrations of artesunate (AS) combined with ferrous iron for 12 h. versus the control; △ versus 512 μg/ml AS; ⋄versus 1024 μg/ml AS.

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